AN OVERARCHING EXPERTISE
Dermatology is a meeting point between our pharmaceutical and dermo-cosmetic R&D teams. It is the cornerstone that captures our desire to be present from“health to beauty.” In the pharmaceutical field, our efforts today focus mainly on infantile hemangioma and onco-dermatological diseases.
Infantile hemangioma is the most common vascular benign tumor of infancy, affecting 3% to 10% of newborns. This benign tumor is characterized by abnormal proliferation of the endothelial tissue. The lesions are rarely detectable at birth and start growing noticeably during the first 4 to 6 weeks of life. Approximately 12% of infantile hemangiomas require treatment. Some infantile hemangiomas based on their location can be functionally impairing (breathing, eating, vision) or life-threatening.
A treatment for infantile hemangioma (IH) was first discovered in 2007 by Dr. Christine Léauté-Labreze, a dermatologist at the Bordeaux University Hospital. In 2009, Pierre Fabre Dermatologie undertook the pharmaceutical and clinical development required to make the discovery accessible to infants with IH, with proven clinical safety and efficacy. In March 2014, the FDA approved the first and only treatment for proliferating infantile hemangioma requiring systemic therapy.
A public health challenge
Skin cancer has been on the rise for 30 years and is now a real public health challenge in terms of both prevention and therapy. It is estimated that in the near future one person in six will develop skin cancer. The individualization of active substances and the development of new topical treatments for these cancers, especially basal-cell carcinoma and actinic keratosis, are more than ever priorities. With our considerable expertise in both oncology and dermatology, onco-dermatology has become a logical focus of research for Pierre Fabre Laboratories.
By maintaining privileged connections with Pierre Fabre’s pharmaceutical research teams and developing numerous partnerships with public research bodies, our dermo-cosmetics researchers have developed indisputable expertise in the related fields of dermatology and cosmetology. In close cooperation with top international specialists they have conducted a number of important clinical studies, thereby contributing to the development of new dermo-cosmetic concepts and to the expansion of knowledge about the skin.